Pulmonary Arterial Hypertension ( Ph ) - 1257 Words

Pulmonary Arterial Hypertension (PAH) belong to group 1 in the classification of Pulmonary Hypertension (PH). It is a chronic progressive disease caused by narrowing of the minor pulmonary arteries due to vascular proliferation and remodeling. Figure 1: Changes occur in blood vessels in PAH. The estimated prevalence for PAH is 15-50 cases per million although it is a rare disease. The female to male ratio is 1.7:1 with higher prevalence between 30-40 years old. To date there are 52 cases per million population of Scotland diagnosed with PAH. (1) The current treatments available for PAH are prostaglandin (PG), calcium channel blocker (CCB), Endothelin Receptor Antagonist (ERA), and Phosphodiesterase-5-inhibitors (PDE-5-I). The need for new drug therapy is due to the drawbacks of the current treatment as shown in the tables below. (3) This has led to the development of Opsumit (Macitentan), a new drug therapy for PAH. Table 1: Drawbacks of using Calcium Channel Blocker (CCB) in PAH Calcium Channel Blocker (Nifedipine, Diltiazem) The proportion of patient benefited from this drug is too little.(2) Table 2: Drawbacks of using Prostaglandins (PGs) in PAH Epoprostenol I.V Iloprost nebulized Treprostinil S.C - Inconvenience administration through IV route which requires hospitalization - Unpresentable body image - Administration of the drug might be associated with high risk of infection (need to be given through continuous I.V infusion due to short half-life)Show MoreRelatedThe Heart Is A Hollow, Muscular Organ Of The Middle Mediastinum Orientated Obliquely961 Words   |  4 Pagesgrooves indicate these divisions: the atria are separated from the ventricles by the coronary sulcus (the atrioventricular groove) with a hiatus anteriorly at the root of the pulmonary artery (PA). 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The right ventricle of the heart is responsible for pumping blood to the pulmonary artery and to the lungs so it can be oxygenated while the left ventricle pumps oxygenated b lood to the tissuesRead MoreHigh Altitude Is Defined As An Elevation Of 1500-3500 Metres1391 Words   |  6 Pagespressure of carbon dioxide, that results in respiratory alkalosis. The body response to respiratory alkalosis by decreasing ventilation, and activating renal compensation by secreting bicarbonate and reabsorbing hydrogen, which gradually brings the blood PH back to normal and allowing an increase in ventilation. The body’s acute hypoxic ventilatory response resulting is renal compensation can take approximately four days before any significant change takes place. In addition to changes in ventilation,Read MoreIncreased Altitude : Adverse Effects On The Cardiopulmonary System1620 Words   |  7 Pagespressure of carbon dioxide, that results in respiratory alkalosis. 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Decreases in pulmonary vasoconstriction through decreases alveolar oxygen tension, as well as increases in pulmonary vascular resistance and pulmonary artery pressure, are seen at this high altitude. †¢ At higher altitudes respiration rate is increased which leads to increases in ventilation (possibly a five-fold increase from sea level). Chemoreceptors in the arterial blood vessels are stimulated to signal the brain to

Analysis of the Stocks of Apple

Question: From the point of view of an investor who wishes to evaluate whether the stocks that you examined are worth investing in, how useful was the analysis you carried out on these stocks? What limitations do you see in your analysis and results for investment decision making purposes? What further analysis would you wish to carry out? Explain. Answer: Effectiveness of the Analysis: The Portfolio analysis of the stocks of Apple, BHP Billiton Ltd. and Citi Group has provided many useful information regarding the profitability and investment risks related to the stocks. Though the present discrete return rate of Apple Inc is showing negative value, the volume of negative rate is nominal and in the recent past the market value of the Apple Inc. stocks has increased significantly. Whereas, the market value of BHP Billiton Ltd. has experienced high up and downs. It indicates that the stock prices of Billiton Ltd. are not stable and consisted with high-risk elements. The prices of the Citi Group stocks have recently fallen greatly, but it has also maintained a steady growth over the recent past. The weighted average rate of return of the three stocks is also quite unstable (Kranner et al. 2015). Hence, amongst the three stocks, it is better to invest in the stocks of Apple Inc. and Citi Group. The BHP Billiton Group can be considered for investment, but, the volume of investment should be minimum to avoid the high risk, connected with the stocks. Limitations of the Analysis: The analytical process, adopted in the report, has not provided any guidance on the proportionate investment. It has given focus on the risk analysis of the individual stocks and the combined rate of return of all three stocks. There is no reference given on how the total investment amount can be divided among the three stocks to segregate the risk factor (Picard 2014). Additional Requirement: Hence, the analysis process should include any diversification method to provide more assistance in the investment decision-making process. Reference List: Kranner, Stephan, Neal Stoughton, and Josef Zechner. "A Natural Experiment in Portfolio Management."Available at SSRN 2514593(2015) Picard, Robert G., ed.Media product portfolios: Issues in management of multiple products and services. Routledge, 2014

The History of Public Relations Essay Example

The History of Public Relations Essay Advanced News Public Relations were discovered in 52 B. C. E. in ancient Rome. It became a profession in the 20th Century in the United States. There, public relations were becoming popular through the development of railroads. It is stimulated in today’s rapid growing business world. The field of Public Relations is a very essential aspect with having a perfect image. Public relations professionals work diligently at creating good and reliable relations between a firm and many different individuals it represents. It deals with a variety of strategies and methods. There are multiple definitions of public relations, which makes it difficult to understand. Public Relation writes, Lattimore, Baskin, Heiman, Toth and Van Leuven provides the definition, Public relations is a leadership and management function that helps achieve organizational objectives, define philosophy, and facilitate organizational change. Public relations practitioners communicate with all relevant internal and external publics to develop positive relationships and to create consistency between organizational goals and societal expectations. Public relations practitioners develop, execute, and evaluate organizational programs that promote the exchange of influence and understanding among an organizations constiuent parts and publics (2004). Edward Bernays was an admirable figure born in Austria in 1892. After attending Cornell in 1912, he began developing his powers of persuasion as a promoter of theatre. Bernays built a career that lasted for four decades, selling consumer products to political candidates. He was a big thinker, and his stratagems were very complex, which drove others to think the way he does. We will write a custom essay sample on The History of Public Relations specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on The History of Public Relations specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on The History of Public Relations specifically for you FOR ONLY $16.38 $13.9/page Hire Writer For example, for the American Tobacco Company Edward persuaded people to think that in order to stay fit smoking will make that possible. He continuously promoted that â€Å"being thin was in†. Even though smoking can never be known as something good, he portrayed it to be a symbol of women’s liberation. That campaign in particular demonstrated Bernays’ innovative thinking and intellectual brilliance. He doesn’t partake in any form of smoking, but was able to persuade thousands to try it, increasing the company’s business. Another strategic approach in this campaign was asking the press to not inform people about the evidence of tobacco’s health risks, even though it was the wrong decision to make. Bernays believed that there was no such thing as bad publicity. The last years of life that he had were spent on getting even greater and his promotional skills to become a legacy in history. Today he is still known as the â€Å"father of public relations† and has left a thumbnail history of the development of the public relations industry in the United States (David). Public Relations have been popular since the twentieth century and were discovered back to ancient civilizations. It is the practice of persuading people through using communicational skills. An example is Edward Bernays who views public relations to be based on the persuasion of attitudes. It is important to have a viewpoint based off of what the majority may find interesting. This will soon target a positive view point from customers. To keep customers satisfied and comfortable with investing money into a company, it is always important to keep their best interest in mind. Through advertising and marketing, the message of the company’s purpose must be clear for customers to understand. Marketing is one of the important fields that are greatly influenced by public relations. Many organizations view public relations to be part of the marketing department. Whether it is under marketing or in its own field, a successful organization requires a well ran public relations department. There are many publics that the PR practitioner must abide by and each is controlled by various communicational skills. Publics that are inside the organizations are managers, clerks, and stock holders. Publics that are outside of the organization will be considered as the government and press. Each of these publics plays a significant role in a well-structured PR organization. There are many functions of public relations that are organizational and social. Organizational functions include: media relations, employee relations, and community relations. These are considered as organizational functions because they sustain a good relationship between the company and their consumers. Media relations focuses more so with the press. It grants the press privileges to advertise an organization the best way possible to gain popularity, which in result makes the company money (Public Relations). Employee relations are about the internal publics of the company. For example, those who work for a company have accurate information on the company’s growth and downfalls to help them excel the company’s performance in the future. Public relations are all about positivity, but are up to the people within the company to carry it out. Last, community relations reflect what the company stands for. It allows for the company to maintain its reputation of good will. The press connects on a marketing basis that insures healthy exposure for the business that is being represented. Maintaining relationships amongst other businesses, strategizing sales plans, and managing inventory of their product are just a few of their duties. They may also be involved in advertising or even in promoting. Marketing communications relates to the field of marketing that includes, constructing displays for promotional events and pamphlets that summarize what the product is and its functions. Marketing communications is what drives the costumers into buying their product. If the sign is appealing to the eye, and if the words that are used are persuading, then the community will buy into the company (Sommerfeldt). Public Relations is based on management, supervisory and technical functions that allows the organization to maintain relationships with other companies to prosper. There are many duties and expectations that public relations have. They include: representing the company well at conferences, attaining honors and awards, conducting business with the press, and having great communicational skills amongst employees (Brigden). Being successful in all four of these areas is not to impress others, but to enhance one’s career in public relations. Also these areas apply not only towards public relations, but also in media relations. Advertising plays a role in public relations, but is not entirely about making a product look appealing to consumers. PR involves informing and educating people and the target group about an organization. Advertising requires having an effective PR. Effective PR develops a bond with the customers to satisfy their needs and to provide good service to leave a good impression (Iyer). This will set growth within the company, making sells increase due to the well- structured effective PR. A very important technique within Public Relations is to control the downfall of the company through five important aspects. They involve: Crisis Detection, Crisis Management, Crisis Communication, Crisis Containment, and Crisis Recovery. I strongly believe my interest in public relations grows more day by day and I strongly believe that I am suitable for a position as such. My skills, abilities, and qualities all together allow me to be qualified at a public relations agency. I possess excellent writing skills, creativity and drive to accomplish all tasks, great organizational skills, multi-tasking ability, and ability to work well as part of a team, accuracy and attention to detail. To sum up I believe that I meet all the requirements to be in public relations. Works Cited 1. Public Relations.   Columbia Electronic Encyclopedia, 6th Edition, (2011): 1. 2. Bridgen,  Liz. Emotional Labour and the Pursuit of the Personal Brand: Public Relations Practitioners Use of Social Media.   Journal of Media Practice V. 12 No. 1 (2011) P. 61-76, 12. 1 (2011): 61-76 3. Conrads,  David. Theres No Such Thing as Bad Publicity.   Christian Science Monitor, 90. 192 (1998): B11-B-1. 4. Dan, Lattimore. Public Relations: the Profession and the Practice. S. l. ]: Mcgraw Hill Higher Education, 2009. Print. 5. Iyer,  Ganesh, David Soberman, and J. Miguel Villas-Boas. The Targeting of Advertising.   Marketing Science, 24. 3 (2005): 461-476. 6. Sommerfeldt,  Erich, and Maureen Taylor. A Social Capital Approach to Improving Public Relations Efficacy: Diagnosing Internal Constraints on External Communication.   Public Relations Review V. 37 No. 3 (September 2011) P. 197-206 , 37. 3 (2011): 197-206. 7. Public Relations.   Columbia Electronic Encyclopedia, 6th Edition, (2011): 1.

The Man in the Iron Mask vs Absolutism Comparative Essay essays

The Man in the Iron Mask vs Absolutism Comparative Essay essays The Man In The Iron Mask: The Absolute Monarchy Of France Revealed The film The Man In The Iron Mask is in part fictional with real historical roots dating back to the age of absolutism. The important people, places and events that shaped all of France are significantly depicted throughout the film. The Man In The Iron Mask portrays an accurate representation of the age of Louis XIV regarding his regime, landscape and courts, as well as French culture. Louis XIVs age of absolutism is mirrored in the film The Man In The Iron Mask. This form of government is called an absolute monarchy where complete authority is given to one person. Born into royalty after his father Louis III, Louis XIV reigned as King of France from 1643 until 1715 as performed by Leonardo Dicaprio. In an absolute state, the King rules by divine right accountable to no one but God. During the film Leonardo remarks to Christine, As King I am ordained by God, I will not go to hell. King Louis XIV ruled over nobility and church, which was essential for him to gain full control with no limits to his power. Louis XIVs desire for wealth, land, power and glory is seen in the eyes of Dicaprio. Louis XIV rated his personal interests and glory highly having nobility praise and dote on him constantly. However, Louis XIV ensured the vitality of France making it the centre for all of Europe blinded by the magnificence of Versailles. Louis XIV was a powerful and feared king w hom gained and kept absolute control over all of France. Louis XIV also built a new court called the Palace of Versailles that reflected his prestige, which sets the scene for The Man In The Iron Mask. The beauty of Versailles is depicted in the film with French Provincial style. Beautiful paintings, marble, gold, tapestries, mirrors, chandeliers, and all elaborate things adorned the rooms and hallways of Versaille ...

Art history- art of romanesque France Coursework

Art history- art of romanesque France - Coursework Example Latin fathers were Cyprian (bishop of Carthage), Tertullian Septimus, Ambrose the bishop of Milan, Jerome, Augustine, the bishop of Hippo and Gregory the great who was the bishop of Rome from 3rd September, 590 to death (Hughs, 2014). Their theological insights greatly shaped the course of the Christian history. These Latin fathers helped in understanding the Christian doctrine development throughout the millennia. Up to the modern era, their explorations of the scriptures have grounded biblical commentary (Lawrence, 2014). 3. Monasticism is whereby one renounces worldly pursuits to devote fully to Christian work. These included monks (male) and nuns (female). Monks and nuns accomplished many practical roles in the middle Ages. They nursed the sick, accommodated travelers, and assisted the poor. The abbots and abbesses offered advice to the secular rulers e.g. the monastery of Cluny under Abbot Odilo an abbot at the secular collegiate church of St. Martins at Tours (Hughs, 2014). Monasticism also offered the society a divine outlet and ideal with vital consequences for the medieval culture wholly. Monasteries also promoted learning, encouraged literacy as well as preserved the features of the ancient literature like the works of Virgil, Cicero, and Aristotle. Monastic composers also had a role in elevating the scope and complexity of choral music as well as creating the best environment for devotion (Lawrence, 2014). 4. The renaissance of the twelfth century had plenty of changes made at the outset of High Middle Ages including political, economic and social transformations with scientific and philosophical roots. The era is characterized by the rediscovery of ancient roman and Greek authors, a rebirth of classical learning as well as the Greek’s spirit of inquiry recovery (Lawrence, 2014). 1. As Duby wrote, in the medieval era, the pilgrimage routes were paths that were walked by kings, princes as well as ordinary peasants. As a result each town along the way

Questions about election maps Article Example | Topics and Well Written Essays - 250 words

Questions about election maps - Article Example The graphics used usually draw quick attention to the viewer and further provides broader parameters of animation. The other type is called the paper map or the static map and majorly signifies stillness in observation. It is more evident that digital online maps presents modern kind of viewer interaction summarized as follows. They can be updated regularly as opposed to static maps which are printed hence not up to date. Creating online maps have reduced the normal production rate. Consequently static maps involve more paper work during creation stages such that it slows down production process. Digital maps also have the ability to contain more information as large data can be downloaded while the static maps cannot contain large files due to the apparent storage limit. On the other hand static maps are found to be valuable in the sense that they provide vital aspects of the original information stored when effecting new changes. I therefore strongly believe in my opinion that digital online maps are more effective compared to static maps. This is majorly because digital maps have moved with the current trend of technology hence represents the modern face of successful invention with utmost accuracy and

Protein Energy Malnutrition Essay Example for Free

Protein Energy Malnutrition Essay The articles subject concerns the protein deficiency among infants in the Osun state of Nigeria. Nursing frequency and duration experienced a reduction during complementary food were introduced to infants in Osun. Mothers tend to be complacent in feeding their babies with complementary food, which result to the minimized breast-feeding of mothers that hinders the natural nutrition that these infants need.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   In a study conducted among Osun infants, they discovered that it was not a advisable for children at this age to be fed by such synthetic food. Consumption of such tends to halt the natural nourishment the babies need from their mothers. As early as two years old, babies were exposed already to complementary food, which is against the requirement of the World Health Organization (Ogunba, 2004). According to WHO, the amount of protein and calories (energy) that were consumed by infants were not above standard levels because these foods contain excess amount of carbohydrates alone (Ogunba, 2004). Obviously, the nutritional requirement of an infant is not met due to the outcome of early supplementation of these synthetic food. Infants natural diet should require constant breast-feeding in which they are enable to consume protein from milk. Unfortunately, this apt nutritional nourishment is ignored by the mothers in Osun (Ogunba, 2004).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   In a study conducted among Osun infants, protein energy malnutrition was discovered that it was in constant depletion. The lack of protein among the infants resulted to â€Å"stunting†. Stunting   has a significant presence in the rural areas, which is an indication of chronic under-nutrition in these areas (Ogunba, 2004). It was discovered that stunting was among the culprits of infant growth faltering, as a result from the consumption of complementary food, children from one to six months of age were experiencing a decrease in growth and health progress (Ogunba, 2004). Stunting is the most prevalent of the different manifestations of PEM (33.9 per cent), followed by underweight (21.0 per cent) and wasting (9.2 per cent) (Ogunba, 2004). Children need protein more than adults do because they are constantly growing and developing. The protein requirement of infants is per unit of body weight higher than those of adults. Reference Ogunba,B. (2004). Protein energy malnutrition in complemented breast-fed babies: implications of   Ã‚  Ã‚  Ã‚  Ã‚   the timing of complementary feeding. Nutrition Food Science. Retrieved February 10,   Ã‚  Ã‚   2008, from   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   http://swtuopproxy.museglobal.com/MuseSessionID=af57a678251afeca8c38cca61826cae/   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   MuseHost=www.emeraldinsight.com/MusePath/Insight/ViewContentServlet?  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Filename=Published/EmeraldFullTextArticle/Articles/0170340504.html